2010927-65-6

2010927-65-6 structure

Name: DPP-4/GPR119 modulator 2
Chemical Name: DPP-4/GPR119 modulator 2
CAS Number: 2010927-65-6
Molecular Formula: C₃₀H₄₀N₈O₃
Molecular Weight: 560.69
Catalog: Signaling Pathways GPCR/G Protein GPR119
Create Date: 2022-07-02 12:12:05
Modify Date: 2024-01-09 12:47:12
DPP-4/GPR119 modulator 2 (Compound 20i) is a dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist with an IC50 of 0.22 µM for DPP-IV and an EC50 of 0.95 µM for GPR119. DPP-4/GPR119 modulator 2 can be used for diabetes research[1].

Name	DPP-4/GPR119 modulator 2

Description	DPP-4/GPR119 modulator 2 (Compound 20i) is a dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist with an IC50 of 0.22 µM for DPP-IV and an EC50 of 0.95 µM for GPR119. DPP-4/GPR119 modulator 2 can be used for diabetes research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase Signaling Pathways >> GPCR/G Protein >> GPR119 Research Areas >> Metabolic Disease
Target	IC50: 0.22 µM (DPP-IV)[1]. EC50: 0.95 µM (GPR119)[1]
References	[1]. Li G, et al. The optimization of xanthine derivatives leading to HBK001 hydrochloride as a potent dual ligand targeting DPP-IV and GPR119. Eur J Med Chem. 2020 Feb 15;188:112017.

Molecular Formula	C₃₀H₄₀N₈O₃
Molecular Weight	560.69