2413649-89-3

2413649-89-3 structure

Name: HBV-IN-23
Chemical Name: HBV-IN-23
CAS Number: 2413649-89-3
Molecular Formula: C₂₅H₂₇N₃O₃S
Molecular Weight: 449.57
Catalog: Signaling Pathways Anti-infection HBV
Create Date: 2022-07-10 20:11:18
Modify Date: 2024-01-10 18:52:28
HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication with an IC50 of 0.58 µM. HBV-IN-23 inhibits HBV DNA replication in both drug sensitive and resistant HBV strains. HBV-IN-23 shows anti-hepatocellular carcinoma cell (HCC) activities. HBV-IN-23 induces HepG2 cells apoptosis[1].

Name	HBV-IN-23

Description	HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication with an IC50 of 0.58 µM. HBV-IN-23 inhibits HBV DNA replication in both drug sensitive and resistant HBV strains. HBV-IN-23 shows anti-hepatocellular carcinoma cell (HCC) activities. HBV-IN-23 induces HepG2 cells apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Target	IC50: 0.58 µM (HBV DNA replication)[1]
References	[1]. Qiu J, et al. Discovery of novel quinazolinone derivatives as potential anti-HBV and anti-HCC agents. Eur J Med Chem. 2020 Nov 1;205:112581.

Molecular Formula	C₂₅H₂₇N₃O₃S
Molecular Weight	449.57