HBV-IN-23

Modify Date: 2024-01-10 18:52:28

HBV-IN-23 Structure
HBV-IN-23 structure
Common Name HBV-IN-23
CAS Number 2413649-89-3 Molecular Weight 449.57
Density N/A Boiling Point N/A
Molecular Formula C25H27N3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HBV-IN-23


HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication with an IC50 of 0.58 µM. HBV-IN-23 inhibits HBV DNA replication in both drug sensitive and resistant HBV strains. HBV-IN-23 shows anti-hepatocellular carcinoma cell (HCC) activities. HBV-IN-23 induces HepG2 cells apoptosis[1].

 Names

Name HBV-IN-23

 HBV-IN-23 Biological Activity

Description HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication with an IC50 of 0.58 µM. HBV-IN-23 inhibits HBV DNA replication in both drug sensitive and resistant HBV strains. HBV-IN-23 shows anti-hepatocellular carcinoma cell (HCC) activities. HBV-IN-23 induces HepG2 cells apoptosis[1].
Related Catalog
Target

IC50: 0.58 µM (HBV DNA replication)[1]

References

[1]. Qiu J, et al. Discovery of novel quinazolinone derivatives as potential anti-HBV and anti-HCC agents. Eur J Med Chem. 2020 Nov 1;205:112581.

 Chemical & Physical Properties

Molecular Formula C25H27N3O3S
Molecular Weight 449.57