2408599-78-8

2408599-78-8 structure
2408599-78-8 structure
  • Name: hCAII-IN-2
  • Chemical Name: hCAII-IN-2
  • CAS Number: 2408599-78-8
  • Molecular Formula: C25H18ClN5O4S
  • Molecular Weight: 519.96
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
  • Create Date: 2022-06-25 21:22:52
  • Modify Date: 2025-08-22 19:42:18
  • hCAII-IN-2 (Compound 11f) is a cytosolic human carbonic anhydrase (hCA) inhibitor with Ki values of 261.4, 3.8, 19.6 and 45.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively[1].

Name hCAII-IN-2
Description hCAII-IN-2 (Compound 11f) is a cytosolic human carbonic anhydrase (hCA) inhibitor with Ki values of 261.4, 3.8, 19.6 and 45.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively[1].
Related Catalog
Target

Ki: 3.8 nM (hCA II), 19.6 nM (hCA IX), 45.2 nM (hCA XII), 261.4 nM (hCA I)[1]

References

[1]. Khalil OM, et al. Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases. Eur J Med Chem. 2020 Feb 15;188:112021.

Molecular Formula C25H18ClN5O4S
Molecular Weight 519.96
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