2451479-57-3

2451479-57-3 structure
2451479-57-3 structure
  • Name: hCAIX-IN-5
  • Chemical Name: hCAIX-IN-5
  • CAS Number: 2451479-57-3
  • Molecular Formula: C18H12FNO3
  • Molecular Weight: 309.29
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
  • Create Date: 2022-07-31 15:38:59
  • Modify Date: 2024-04-08 11:13:50
  • hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].

Name hCAIX-IN-5
Description hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].
Related Catalog
Target

KI: >10000 nM (hCAI); >10000 nM (hCAII); 130.7 nM (hCAIV); 829.1 nM (hCAIX)[1]

References

[1]. Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28(15):115586.

Molecular Formula C18H12FNO3
Molecular Weight 309.29
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