hCAIX-IN-5

Modify Date: 2025-08-29 02:48:45

hCAIX-IN-5 Structure
hCAIX-IN-5 structure
Common Name hCAIX-IN-5
CAS Number 2451479-57-3 Molecular Weight 309.29
Density N/A Boiling Point N/A
Molecular Formula C18H12FNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of hCAIX-IN-5


hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].

 Names

Name hCAIX-IN-5

 hCAIX-IN-5 Biological Activity

Description hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].
Related Catalog
Target

KI: >10000 nM (hCAI); >10000 nM (hCAII); 130.7 nM (hCAIV); 829.1 nM (hCAIX)[1]

References

[1]. Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28(15):115586.

 Chemical & Physical Properties

Molecular Formula C18H12FNO3
Molecular Weight 309.29
InChIKey MJJVZWVJDKKFDF-YCRREMRBSA-N
SMILES O=C(C=Cc1ccc(F)cc1)Nc1ccc2oc(=O)ccc2c1
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