2525173-96-8

2525173-96-8 structure

Name: HIV-1 protease-IN-5
Chemical Name: HIV-1 protease-IN-5
CAS Number: 2525173-96-8
Molecular Formula: C₂₇H₂₉F₃N₂O₇S
Molecular Weight: 582.59
Catalog: Signaling Pathways Metabolic Enzyme/Protease HIV Protease
Create Date: 2022-07-01 16:25:06
Modify Date: 2024-01-11 09:19:35
HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants[1].

Name	HIV-1 protease-IN-5

Description	HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease
Target	IC50: 1.64 nM (HIV-1 protease)[1]
References	[1]. Zhu M, et al. Design and biological evaluation of novel HIV-1 protease inhibitors with isopropanol as P1' ligand to enhance binding with S1' subsite. Bioorg Med Chem. 2020 Aug 15;28(16):115623.

Molecular Formula	C₂₇H₂₉F₃N₂O₇S
Molecular Weight	582.59