HIV-1 protease-IN-5

Modify Date: 2024-01-11 09:19:35

HIV-1 protease-IN-5 Structure
HIV-1 protease-IN-5 structure
Common Name HIV-1 protease-IN-5
CAS Number 2525173-96-8 Molecular Weight 582.59
Density N/A Boiling Point N/A
Molecular Formula C27H29F3N2O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-1 protease-IN-5


HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants[1].

 Names

Name HIV-1 protease-IN-5

 HIV-1 protease-IN-5 Biological Activity

Description HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants[1].
Related Catalog
Target

IC50: 1.64 nM (HIV-1 protease)[1]

References

[1]. Zhu M, et al. Design and biological evaluation of novel HIV-1 protease inhibitors with isopropanol as P1' ligand to enhance binding with S1' subsite. Bioorg Med Chem. 2020 Aug 15;28(16):115623.

 Chemical & Physical Properties

Molecular Formula C27H29F3N2O7S
Molecular Weight 582.59