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2230055-52-2

2230055-52-2 structure
2230055-52-2 structure
  • Name: PKCiota-IN-2
  • Chemical Name: PKCiota-IN-2
  • CAS Number: 2230055-52-2
  • Molecular Formula: C24H21N5O
  • Molecular Weight: 395.46
  • Catalog: Signaling Pathways Epigenetics PKC
  • Create Date: 2022-06-30 00:43:31
  • Modify Date: 2024-01-16 14:39:45
  • PKCiota-IN-2 is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively[1].

Name PKCiota-IN-2
Description PKCiota-IN-2 is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively[1].
Related Catalog
Target

PKCι:2.8 nM (IC50)

PKCα:71 nM (IC50)

PKCε:350 nM (IC50)

References

[1]. Jacek Kwiatkowski, et al. Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors. J Med Chem. 2018 May 24;61(10):4386-4396.

Molecular Formula C24H21N5O
Molecular Weight 395.46