2245820-70-4

2245820-70-4 structure
2245820-70-4 structure
  • Name: RIPK2-IN-1
  • Chemical Name: RIPK2-IN-1
  • CAS Number: 2245820-70-4
  • Molecular Formula: C23H27N5O3S
  • Molecular Weight: 453.56
  • Catalog: Signaling Pathways Apoptosis RIP kinase
  • Create Date: 2022-07-11 08:45:51
  • Modify Date: 2024-01-14 13:14:02
  • RIPK2-IN-1 (compound 18f) is a potent RIPK2 inhibitor with an IC50 of 51 nM. RIPK2-IN-1 inhibits ALK2 with an IC50 of 5 nM. RIPK2-IN-1 has an IC50 of 390 nM on RIPK2/NOD2 in cell assay[1].

Name RIPK2-IN-1
Description RIPK2-IN-1 (compound 18f) is a potent RIPK2 inhibitor with an IC50 of 51 nM. RIPK2-IN-1 inhibits ALK2 with an IC50 of 5 nM. RIPK2-IN-1 has an IC50 of 390 nM on RIPK2/NOD2 in cell assay[1].
Related Catalog
References

[1]. Chalada Suebsuwong, et al. Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. Eur J Med Chem. 2020 Aug 15;200:112417.

Molecular Formula C23H27N5O3S
Molecular Weight 453.56
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