2128651-12-5

2128651-12-5 structure

Name: SIRT5 inhibitor 3
Chemical Name: SIRT5 inhibitor 3
CAS Number: 2128651-12-5
Molecular Formula: C₂₂H₁₂FN₃O₄
Molecular Weight: 401.35
Catalog: Signaling Pathways Cell Cycle/DNA Damage Sirtuin
Create Date: 2022-07-02 12:52:07
Modify Date: 2025-08-25 18:48:15
SIRT5 inhibitor 3 (compound 46) is a potent and competitive SIRT5 inhibitor with an IC50 value of 5.9 μM. SIRT5 inhibitor 3 can inhibit SIRT5 desuccinylation. SIRT5 inhibitor 3 can be used for researching cancer and neurodegenerative diseases[1].

Name	SIRT5 inhibitor 3

Description	SIRT5 inhibitor 3 (compound 46) is a potent and competitive SIRT5 inhibitor with an IC50 value of 5.9 μM. SIRT5 inhibitor 3 can inhibit SIRT5 desuccinylation. SIRT5 inhibitor 3 can be used for researching cancer and neurodegenerative diseases[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Research Areas >> Neurological Disease
Target	SIRT5:5.9 μM (IC50)
References	[1]. Wang Y, et al. Overview of SIRT5 as a potential therapeutic target: Structure, function and inhibitors. Eur J Med Chem. 2022;236:114363.

Molecular Formula	C₂₂H₁₂FN₃O₄
Molecular Weight	401.35