2260669-11-0

2260669-11-0 structure

Name: 7α,25-Dihydroxycholesterol-d6
Chemical Name: 7α,25-Dihydroxycholesterol-d6
CAS Number: 2260669-11-0
Molecular Formula: C₂₇H₄₀D₆O₃
Molecular Weight: 424.69
Catalog: Signaling Pathways GPCR/G Protein EBI2/GPR183
Create Date: 2022-08-10 13:45:18
Modify Date: 2024-01-14 20:30:34
7α,25-Dihydroxycholesterol-d6 is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly

Name	7α,25-Dihydroxycholesterol-d6

Description	7α,25-Dihydroxycholesterol-d6 is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> EBI2/GPR183
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
References	[1]. Liu C, et al. Oxysterols direct B-cell migration through EBI2. Nature. 2011 Jul 27;475(7357):519-23. [2]. Hannedouche S, et al. Oxysterols direct immune cell migration via EBI2. Nature. 2011 Jul 27;475(7357):524-7. [3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Molecular Formula	C₂₇H₄₀D₆O₃
Molecular Weight	424.69