2410402-82-1

2410402-82-1 structure

Name: CDK2-IN-11
Chemical Name: CDK2-IN-11
CAS Number: 2410402-82-1
Molecular Formula: C₁₈H₁₄ClN₇O₂S
Molecular Weight: 427.87
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2022-08-03 17:56:58
Modify Date: 2025-08-30 16:30:57
CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer[1].

Name	CDK2-IN-11

Description	CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	IC50: 6.4 μM (CDK2)[1] KI: 23.4 nM (hCA II), 56.3 nM (hCA IX), 44.3 nM (hCA XII)[1]
References	[1]. Said MA, et al. Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation. Eur J Med Chem. 2020 Mar 1;189:112019.

Molecular Formula	C₁₈H₁₄ClN₇O₂S
Molecular Weight	427.87