CDK2-IN-11

Modify Date: 2025-08-30 16:30:57

CDK2-IN-11 Structure
CDK2-IN-11 structure
Common Name CDK2-IN-11
CAS Number 2410402-82-1 Molecular Weight 427.87
Density N/A Boiling Point N/A
Molecular Formula C18H14ClN7O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK2-IN-11


CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer[1].

 Names

Name CDK2-IN-11

 CDK2-IN-11 Biological Activity

Description CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer[1].
Related Catalog
Target

IC50: 6.4 μM (CDK2)[1] KI: 23.4 nM (hCA II), 56.3 nM (hCA IX), 44.3 nM (hCA XII)[1]

References

[1]. Said MA, et al. Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation. Eur J Med Chem. 2020 Mar 1;189:112019.

 Chemical & Physical Properties

Molecular Formula C18H14ClN7O2S
Molecular Weight 427.87
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