2636771-45-2
2636771-45-2 structure
- Name: IZTZ-1
- Chemical Name: IZTZ-1
- CAS Number: 2636771-45-2
- Molecular Formula: C32H35N7S
- Molecular Weight: 549.73
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2022-08-11 13:03:34
- Modify Date: 2026-10-06 12:05:49
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IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research[1].
| Name | IZTZ-1 |
|---|---|
| Synonyms | Benzothiazole, 2-[4,5-bis[4-(4-methyl-1-piperazinyl)phenyl]-1H-imidazol-2-yl] |
| Description | IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research[1]. |
|---|---|
| Related Catalog | |
| In Vivo | IZTZ-1 (0-20 mg/kg, IP, once every two days, for 10 days) effectively inhibits tumor growth in a melanoma mouse model[1]. |
| References |
| Molecular Formula | C32H35N7S |
|---|---|
| Molecular Weight | 549.73 |