IZTZ-1

Modify Date: 2024-02-04 10:15:28

IZTZ-1 Structure
IZTZ-1 structure
Common Name IZTZ-1
CAS Number 2636771-45-2 Molecular Weight 549.73
Density N/A Boiling Point N/A
Molecular Formula C32H35N7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IZTZ-1


IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research[1].

 Names

Name IZTZ-1

 IZTZ-1 Biological Activity

Description IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research[1].
Related Catalog
In Vivo IZTZ-1 (0-20 mg/kg, IP, once every two days, for 10 days) effectively inhibits tumor growth in a melanoma mouse model[1].
References

[1]. Wu TY, et al. A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex. Bioorg Chem. 2020 Jun;99:103866.

 Chemical & Physical Properties

Molecular Formula C32H35N7S
Molecular Weight 549.73
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

IZTZ-1 suppliers

IZTZ-1 price