2492595-24-9

2492595-24-9 structure

Name: MRGPRX4 modulator-2
Chemical Name: MRGPRX4 modulator-2
CAS Number: 2492595-24-9
Molecular Formula: C₁₅H₉ClF₄O₃
Molecular Weight: 348.68
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-08-16 11:54:47
Modify Date: 2025-08-26 15:04:07
MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1].

Name	MRGPRX4 modulator-2

Description	MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: < 100 nM (MRGPR X4)[1]
References	[1]. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55)

Molecular Formula	C₁₅H₉ClF₄O₃
Molecular Weight	348.68