1223378-42-4

1223378-42-4 structure

1223378-42-4 structure

Name: Nampt-IN-7
Chemical Name: Nampt-IN-7
CAS Number: 1223378-42-4
Molecular Formula: C₂₀H₂₁N₅O₃
Molecular Weight: 379.41
Catalog: Signaling Pathways Metabolic Enzyme/Protease Nampt
Create Date: 2022-08-04 19:16:24
Modify Date: 2024-01-10 08:41:49
Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].

Name	Nampt-IN-7

Description	Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Nampt
Target	IC50: 7.31 ± 1.59 μM (NAMPT)[1]
References	[1]. Ozgencil F, et al. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. Bioorg Med Chem. 2020 Jan 1;28(1):115217.

Molecular Formula	C₂₀H₂₁N₅O₃
Molecular Weight	379.41