1223378-42-4

1223378-42-4 structure
1223378-42-4 structure
  • Name: Nampt-IN-7
  • Chemical Name: Nampt-IN-7
  • CAS Number: 1223378-42-4
  • Molecular Formula: C20H21N5O3
  • Molecular Weight: 379.41
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Nampt
  • Create Date: 2022-08-04 19:16:24
  • Modify Date: 2025-08-26 13:17:09
  • Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].

Name Nampt-IN-7
Description Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].
Related Catalog
Target

IC50: 7.31 ± 1.59 μM (NAMPT)[1]

References

[1]. Ozgencil F, et al. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. Bioorg Med Chem. 2020 Jan 1;28(1):115217.

Molecular Formula C20H21N5O3
Molecular Weight 379.41
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