Nampt-IN-7

Modify Date: 2025-08-26 13:17:09

Nampt-IN-7 Structure
Nampt-IN-7 structure
Common Name Nampt-IN-7
CAS Number 1223378-42-4 Molecular Weight 379.41
Density N/A Boiling Point N/A
Molecular Formula C20H21N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nampt-IN-7


Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].

 Names

Name Nampt-IN-7

 Nampt-IN-7 Biological Activity

Description Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].
Related Catalog
Target

IC50: 7.31 ± 1.59 μM (NAMPT)[1]

References

[1]. Ozgencil F, et al. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. Bioorg Med Chem. 2020 Jan 1;28(1):115217.

 Chemical & Physical Properties

Molecular Formula C20H21N5O3
Molecular Weight 379.41
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