2180973-35-5

2180973-35-5 structure
2180973-35-5 structure
  • Name: Nampt-IN-9
  • Chemical Name: Nampt-IN-9
  • CAS Number: 2180973-35-5
  • Molecular Formula: C26H33N3O4
  • Molecular Weight: 451.56
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Nampt
  • Create Date: 2022-08-04 10:54:23
  • Modify Date: 2024-01-10 09:12:02
  • Nampt-IN-9 (Compound 8) is a potent NAMPT inhibitor with anticancer activities. Nampt-IN-9 can be used for pancreatic ductal adenocarcinoma research[1].

Name Nampt-IN-9
Description Nampt-IN-9 (Compound 8) is a potent NAMPT inhibitor with anticancer activities. Nampt-IN-9 can be used for pancreatic ductal adenocarcinoma research[1].
Related Catalog
In Vitro Nampt-IN-9 (Compound 8) shows anti-proliferative activity with IC50 values of 0.8, 0.5, 0.004 and 0.6 nM against Jurkat, MIA PaCa-2, BxPC-3, PANC-1 cells, respectively[1]. Nampt-IN-9 (0-1 μM) blunts NAD+ and ATP levels and activates caspase 3 in Jurkat leukemia cells[1].
References

[1]. Bai JF, et al. Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer. Eur J Med Chem. 2022 Jun 2;239:114504.

Molecular Formula C26H33N3O4
Molecular Weight 451.56