Nampt-IN-9

Modify Date: 2024-01-10 09:12:02

Nampt-IN-9 structure	Common Name	Nampt-IN-9
	CAS Number	2180973-35-5	Molecular Weight	451.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₃N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Nampt-IN-9

Nampt-IN-9 (Compound 8) is a potent NAMPT inhibitor with anticancer activities. Nampt-IN-9 can be used for pancreatic ductal adenocarcinoma research[1].

Name	Nampt-IN-9

Description	Nampt-IN-9 (Compound 8) is a potent NAMPT inhibitor with anticancer activities. Nampt-IN-9 can be used for pancreatic ductal adenocarcinoma research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Nampt
In Vitro	Nampt-IN-9 (Compound 8) shows anti-proliferative activity with IC50 values of 0.8, 0.5, 0.004 and 0.6 nM against Jurkat, MIA PaCa-2, BxPC-3, PANC-1 cells, respectively[1]. Nampt-IN-9 (0-1 μM) blunts NAD+ and ATP levels and activates caspase 3 in Jurkat leukemia cells[1].
References	[1]. Bai JF, et al. Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer. Eur J Med Chem. 2022 Jun 2;239:114504.

Molecular Formula	C₂₆H₃₃N₃O₄
Molecular Weight	451.56