2387678-02-4
2387678-02-4 structure
- Name: TGFβ-IN-2
- Chemical Name: TGFβ-IN-2
- CAS Number: 2387678-02-4
- Molecular Formula: C22H22N2O4
- Molecular Weight: 378.42
- Catalog: Signaling Pathways Stem Cell/Wnt TGF-beta/Smad
- Create Date: 2022-08-02 21:09:21
- Modify Date: 2025-08-19 17:00:47
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TGFβ-IN-2 (Compound 9d) inhibits TGF-β-induced total collagen accumulation in NRK-49F cells with the IC50 of 4.31 μM. TGFβ-IN-2 suppresses the TGF-β-induced protein expression of COL1A1, α-SMA, and p-Smad3 in vitro. TGFβ-IN-2 can be used as a potential effective compound for anti-fibrosis in vivo by oral administration[1].
| Name | TGFβ-IN-2 |
|---|
| Description | TGFβ-IN-2 (Compound 9d) inhibits TGF-β-induced total collagen accumulation in NRK-49F cells with the IC50 of 4.31 μM. TGFβ-IN-2 suppresses the TGF-β-induced protein expression of COL1A1, α-SMA, and p-Smad3 in vitro. TGFβ-IN-2 can be used as a potential effective compound for anti-fibrosis in vivo by oral administration[1]. |
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| Molecular Formula | C22H22N2O4 |
|---|---|
| Molecular Weight | 378.42 |