2697171-03-0

2697171-03-0 structure

Name: Topoisomerase II inhibitor 7
Chemical Name: Topoisomerase II inhibitor 7
CAS Number: 2697171-03-0
Molecular Formula: C₃₂H₂₈BrN₅O₅S
Molecular Weight: 674.56
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-08-10 18:21:27
Modify Date: 2024-01-09 16:23:45
Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis[1].

Name	Topoisomerase II inhibitor 7

Description	Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target	topoisomerase II alpha:3.19 μM (IC50)
References	[1]. Nemr MTM, et, al. Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity. Bioorg Chem. 2020 Dec;105:104446.

Molecular Formula	C₃₂H₂₈BrN₅O₅S
Molecular Weight	674.56