Topoisomerase II inhibitor 7

Modify Date: 2024-01-09 16:23:45

Topoisomerase II inhibitor 7 Structure
Topoisomerase II inhibitor 7 structure
Common Name Topoisomerase II inhibitor 7
CAS Number 2697171-03-0 Molecular Weight 674.56
Density N/A Boiling Point N/A
Molecular Formula C32H28BrN5O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Topoisomerase II inhibitor 7


Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis[1].

 Names

Name Topoisomerase II inhibitor 7

 Topoisomerase II inhibitor 7 Biological Activity

Description Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis[1].
Related Catalog
Target

topoisomerase II alpha:3.19 μM (IC50)

References

[1]. Nemr MTM, et, al. Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity. Bioorg Chem. 2020 Dec;105:104446.

 Chemical & Physical Properties

Molecular Formula C32H28BrN5O5S
Molecular Weight 674.56
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