Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NSC 698600
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Purity: 98.0%
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908069-17-0

908069-17-0 structure

908069-17-0 structure

Name: NSC 698600
Chemical Name: NSC 698600
CAS Number: 908069-17-0
Molecular Formula: C₁₄H₁₂N₂O₂S
Molecular Weight: 272.32
Catalog: Signaling Pathways Epigenetics Histone Acetyltransferase
Create Date: 2022-09-24 20:49:04
Modify Date: 2024-01-19 19:14:43
NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 µM (PCAF/H31-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells[1].

Name	NSC 698600

Description	NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 µM (PCAF/H31-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Acetyltransferase
Target	IC50: 6.51 µM (PCAF/H31-21)[1].
In Vitro	NSC 698600 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells[1]. Cell Proliferation Assay[1] Cell Line: SK-N-SH, HCT116 cells Concentration: 25 µM Incubation Time: 72 h Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI50 of 12.2 µM and growth inhibition of 40%, respectively.
References	[1]. Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89.

Molecular Formula	C₁₄H₁₂N₂O₂S
Molecular Weight	272.32

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