1940128-37-9
1940128-37-9 structure
- Name: IDH1 Inhibitor 5
- Chemical Name: IDH1 Inhibitor 5
- CAS Number: 1940128-37-9
- Molecular Formula: C26H34N4O3
- Molecular Weight: 450.57
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Isocitrate Dehydrogenase (IDH)
- Create Date: 2022-10-08 10:12:00
- Modify Date: 2024-01-12 19:08:36
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IDH1 Inhibitor 5 (compound 2) is an IDH1 (isocitrate dehydrogenase 1) inhibitor. IDH1 Inhibitor 5 inhibits MOG cells and wild-type IDH1 glioma cells with expressing exogenous mutant IDH1 R132H protein with IC50s of 64.4 and 34.9 nM, respectively[1].
| Name | IDH1 Inhibitor 5 |
|---|
| Description | IDH1 Inhibitor 5 (compound 2) is an IDH1 (isocitrate dehydrogenase 1) inhibitor. IDH1 Inhibitor 5 inhibits MOG cells and wild-type IDH1 glioma cells with expressing exogenous mutant IDH1 R132H protein with IC50s of 64.4 and 34.9 nM, respectively[1]. |
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| Related Catalog | |
| Target |
IC50: 64.4 nM (MOG cells), 34.9 nM (wild-type IDH1 glioma cells with expressing exogenous mutant IDH1 R132H protein)[1] |
| In Vitro | IDH1 Inhibitor 5 (0-10 μM; 1 h) shows cellular potency in MOG cells[1]. Cell Cytotoxicity Assay[1] Cell Line: MOG cell line and wild-type IDH1 glioma cells with expressing exogenous mutant IDH1 R132H protein Concentration: 0-10 μM Incubation Time: 1 hour Result: Showed cellular potency to MOG cells and wild-type IDH1 glioma cells with expressing exogenous mutant IDH1 R132H protein with IC50s of 64.4 and 34.9 nM, respectively. |
| References |
| Molecular Formula | C26H34N4O3 |
|---|---|
| Molecular Weight | 450.57 |