2232890-86-5

2232890-86-5 structure

2232890-86-5 structure

Name: TK4g
Chemical Name: TK4g
CAS Number: 2232890-86-5
Molecular Formula: C₁₉H₁₉N₃O₄S
Molecular Weight: 385.44
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2022-10-22 17:52:57
Modify Date: 2024-04-05 17:38:28
TK4g is a Janus kinase (JAK) inhibitor with the IC50 values of 12.61 nM and 15.80 nM for JAK2 and JAK3, respectively. TK4g can be used in lymphoid-derived diseases and leukemia cancer research[1].

Name	TK4g

Description	TK4g is a Janus kinase (JAK) inhibitor with the IC50 values of 12.61 nM and 15.80 nM for JAK2 and JAK3, respectively. TK4g can be used in lymphoid-derived diseases and leukemia cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	JAK2:12.61 nM (IC50) JAK3:15.80 nM (IC50)
References	[1]. Kamonpan Sanachai, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega 2022.

Molecular Formula	C₁₉H₁₉N₃O₄S
Molecular Weight	385.44