272108-04-0

272108-04-0 structure
272108-04-0 structure
  • Name: Oleana-2,12-dien-28-oic acid
  • Chemical Name: Oleana-2,12-dien-28-oic acid
  • CAS Number: 272108-04-0
  • Molecular Formula: C30H46O2
  • Molecular Weight: 438.68
  • Catalog: Signaling Pathways Anti-infection HBV
  • Create Date: 2022-11-03 11:09:19
  • Modify Date: 2024-10-01 09:22:51
  • Oleana-2,12-dien-28-oic acid is an HBV-DNA inhibitor, HBsAg and HBeAg inhibitor. Oleana-2,12-dien-28-oic acid can be used in hepatitis B virus infection disease research[1].

Name Oleana-2,12-dien-28-oic acid
Description Oleana-2,12-dien-28-oic acid is an HBV-DNA inhibitor, HBsAg and HBeAg inhibitor. Oleana-2,12-dien-28-oic acid can be used in hepatitis B virus infection disease research[1].
Related Catalog
In Vitro Oleana-2,12-dien-28-oic acid (4-100 μg/mL; 7 d) shows the inhibition on hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) secreted by HepG2.2.15 cells[1]. Oleana-2,12-dien-28-oic acid (4-100 μg/mL; 7 d) inhibits the replication of hepatitis B virus deoxyribonucleic acid (HBV-DNA) of HepG2.2.15 cells[1]. Cell Viability Assay[1] Cell Line: HepG2 .2 .15 cells Concentration: 4, 20, 100 μg/mL Incubation Time: 7 days Result: Inhibited hepatitis B surface antigen (HBsAg) of 60.5%, 69.8%, and 85.3% at 4, 20, and 100 μg/mL, respectively. Inhibited hepatitis B e antigen (HBeAg) of 45.1%, 60.5%, and 76.9% at 4, 20, and 100 μg/mL, respectively.
References

[1]. Wu XM, et al. Medical application of A-ring double-bond oleanolic acid in preparation of medicines for preventing and treating viral hepatitis B. CN111759846A.

Molecular Formula C30H46O2
Molecular Weight 438.68
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