381717-91-5
381717-91-5 structure
- Name: p53-MDM2-IN-1
- Chemical Name: WAY-226055
- CAS Number: 381717-91-5
- Molecular Formula: C23H20ClN3O3
- Molecular Weight: 421.88
- Catalog: Signaling Pathways Apoptosis MDM-2/p53
- Create Date: 2022-11-26 14:49:27
- Modify Date: 2024-04-06 16:52:16
-
p53-MDM2-IN-1 (Example 30) is an inhibitor of p53-MDM2/X protein interaction with an Ki value of 23.35 µM. p53-MDM2-IN-1 can be used for anti-tumor research[1].
| Name | WAY-226055 |
|---|---|
| Synonyms |
4-Benzoyl-5-(4-chlorophenyl)-3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]-1,5-dihydro-2H-pyrrol-2-one
MFCD01819429 2H-Pyrrol-2-one, 4-benzoyl-5-(4-chlorophenyl)-1,5-dihydro-3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]- |
| Description | p53-MDM2-IN-1 (Example 30) is an inhibitor of p53-MDM2/X protein interaction with an Ki value of 23.35 µM. p53-MDM2-IN-1 can be used for anti-tumor research[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Zhang W, et al. Pyrrylketone compound and application thereof as drug. China. CN102603717. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 686.1±55.0 °C at 760 mmHg |
| Molecular Formula | C23H20ClN3O3 |
| Molecular Weight | 421.88 |
| Flash Point | 368.7±31.5 °C |
| Exact Mass | 421.119324 |
| LogP | 3.40 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.659 |