663213-98-7
663213-98-7 structure
- Name: Wnt pathway inhibitor 3
- Chemical Name: WAY-324166
- CAS Number: 663213-98-7
- Molecular Formula: C21H17BrN2O5
- Molecular Weight: 457.27
- Create Date: 2022-12-17 18:39:54
- Modify Date: 2023-10-20 17:39:35
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Wnt pathway inhibitor 3 is a potent wnt inhibitor with an IC50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity[1].
| Name | WAY-324166 |
|---|---|
| Synonyms |
8-[4-(Allyloxy)-3-bromo-5-methoxyphenyl]-6-amino-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
8H-1,3-Dioxolo[4,5-g][1]benzopyran-7-carbonitrile, 6-amino-8-[3-bromo-5-methoxy-4-(2-propen-1-yloxy)phenyl]- |
| Description | Wnt pathway inhibitor 3 is a potent wnt inhibitor with an IC50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 45 nM (wnt)[1] |
| In Vitro | Wnt pathway inhibitor 3 (compound 41) (0-100 000nM; 72 h) 显示抗增殖活性，对 HS68、Dld1、HCT116、SW480 细胞的 IC50 值分别为 641、470、551、618 nM[1]。 |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 587.0±50.0 °C at 760 mmHg |
| Molecular Formula | C21H17BrN2O5 |
| Molecular Weight | 457.27 |
| Flash Point | 308.8±30.1 °C |
| Exact Mass | 456.032074 |
| LogP | 4.14 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.679 |