Wnt pathway inhibitor 3

Modify Date: 2023-10-20 17:39:35

Wnt pathway inhibitor 3 Structure
Wnt pathway inhibitor 3 structure
Common Name Wnt pathway inhibitor 3
CAS Number 663213-98-7 Molecular Weight 457.27
Density 1.6±0.1 g/cm3 Boiling Point 587.0±50.0 °C at 760 mmHg
Molecular Formula C21H17BrN2O5 Melting Point N/A
MSDS N/A Flash Point 308.8±30.1 °C

 Use of Wnt pathway inhibitor 3


Wnt pathway inhibitor 3 is a potent wnt inhibitor with an IC50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity[1].

 Names

Name WAY-324166
Synonym More Synonyms

 Wnt pathway inhibitor 3 Biological Activity

Description Wnt pathway inhibitor 3 is a potent wnt inhibitor with an IC50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity[1].
Related Catalog
Target

IC50: 45 nM (wnt)[1]

In Vitro Wnt pathway inhibitor 3 (compound 41) (0-100 000nM; 72 h) 显示抗增殖活性,对 HS68、Dld1、HCT116、SW480 细胞的 IC50 值分别为 641、470、551、618 nM[1]。
References

[1]. Michael Boutros, et al. Chromene derivatives and their analoga as wnt pathway antagonists. US20130296344A1.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 587.0±50.0 °C at 760 mmHg
Molecular Formula C21H17BrN2O5
Molecular Weight 457.27
Flash Point 308.8±30.1 °C
Exact Mass 456.032074
LogP 4.14
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.679

 Synonyms

8-[4-(Allyloxy)-3-bromo-5-methoxyphenyl]-6-amino-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
8H-1,3-Dioxolo[4,5-g][1]benzopyran-7-carbonitrile, 6-amino-8-[3-bromo-5-methoxy-4-(2-propen-1-yloxy)phenyl]-
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