Top Suppliers:I want be here

  • DC Chemicals Limited
  • China
  • Product Name: CDN-A
  • Price: ¥Inquiry/100mg ¥Inquiry/250mg ¥Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Tony Cao

2586047-09-6

2586047-09-6 structure
2586047-09-6 structure
  • Name: CDN-A
  • Chemical Name: CDN-A
  • CAS Number: 2586047-09-6
  • Molecular Formula: C22H29N11O12P2
  • Molecular Weight: 701.48
  • Catalog: Signaling Pathways Immunology/Inflammation STING
  • Create Date: 2023-01-27 01:58:25
  • Modify Date: 2024-04-05 20:10:38
  • CDN-A is a cyclic di-nucleotide, it can be used to synthesis antibody-drug conjugate (ADC). Cyclic di-nucleotides are potent stimulators of innate and adaptive immune responses. In humans, cyclic di-nucleotide, which are either produced endogenously in response to foreign DNA or by invading bacterial pathogens, trigger the innate immune system by activating the expression of interferon genes[1][2][3].

Name CDN-A
Description CDN-A is a cyclic di-nucleotide, it can be used to synthesis antibody-drug conjugate (ADC). Cyclic di-nucleotides are potent stimulators of innate and adaptive immune responses. In humans, cyclic di-nucleotide, which are either produced endogenously in response to foreign DNA or by invading bacterial pathogens, trigger the innate immune system by activating the expression of interferon genes[1][2][3].
Related Catalog
References

[1]. Chen, Zhijian, et al. Antinbody-sting agonist conjugates and their use in immunotherapy. US 2021/0015941 Al. 2021.

[2]. Lirussi D, et al. Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway. EBioMedicine. 2017 Aug;22:100-111.  

[3]. Schaap P. Cyclic di-nucleotide signaling enters the eukaryote domain. IUBMB Life. 2013 Nov;65(11):897-903.  

Molecular Formula C22H29N11O12P2
Molecular Weight 701.48