2616562-74-2

2616562-74-2 structure
2616562-74-2 structure
  • Name: Fmoc-L-Asn(EDA-N3)-OH
  • Chemical Name: Fmoc-L-Asn(EDA-N3)-OH
  • CAS Number: 2616562-74-2
  • Molecular Formula: C21H21N5O5
  • Molecular Weight: 423.42
  • Catalog: Research Areas Others
  • Create Date: 2023-02-08 19:30:14
  • Modify Date: 2024-04-02 12:28:28
  • Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II[1].

Name Fmoc-L-Asn(EDA-N3)-OH
Description Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II[1].
Related Catalog
References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

Molecular Formula C21H21N5O5
Molecular Weight 423.42