2616562-74-2

2616562-74-2 structure

Name: Fmoc-L-Asn(EDA-N3)-OH
Chemical Name: Fmoc-L-Asn(EDA-N3)-OH
CAS Number: 2616562-74-2
Molecular Formula: C₂₁H₂₁N₅O₅
Molecular Weight: 423.42
Catalog: Research Areas Others
Create Date: 2023-02-08 19:30:14
Modify Date: 2024-04-02 12:28:28
Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II[1].

Name	Fmoc-L-Asn(EDA-N3)-OH

Description	Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.

Molecular Formula	C₂₁H₂₁N₅O₅
Molecular Weight	423.42