1200440-65-8

1200440-65-8 structure

Name: Insulin peglispro
Chemical Name: Insulin peglispro
CAS Number: 1200440-65-8
Molecular Formula: C₃₇₀H₅₆₆N₁₀₄O₁₁₀S₄
Molecular Weight: 8359.32
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Insulin Receptor
Create Date: 2023-01-25 17:07:44
Modify Date: 2024-01-03 16:12:09
Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins[1].

Name	Insulin peglispro

Description	Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor
In Vivo	Insulin peglispro (BIL) (s.c., 17, 0.45 or 1.15 mg/kg/d, 52 week) 在任何剂量下对Crl:CD(SD)大鼠的生存没有影响，会导致体重有些增加。在给药剂量为 0.17 mg/kg时，血清葡萄糖浓度没有影响，而 0.45 mg/kg 时，在第 1 天给药后 3 小时和 6 小时显示出较低的血清葡萄糖浓度[1]。
References	[1]. Richard A Byrd, et al. Chronic Toxicology Studies of Basal Insulin Peglispro in Rats and Dogs: A Novel, PEGylated Insulin Lispro Analog with a Prolonged Duration of Action. Toxicol Pathol. 2017 Apr;45(3):402-415.

Molecular Formula	C₃₇₀H₅₆₆N₁₀₄O₁₁₀S₄
Molecular Weight	8359.32