2812352-99-9

2812352-99-9 structure

Name: MALT1-IN-11
Chemical Name: MALT1-IN-11
CAS Number: 2812352-99-9
Molecular Formula: C₂₀H₁₆F₄N₈O
Molecular Weight: 460.39
Catalog: Signaling Pathways NF-κB MALT1
Create Date: 2023-04-05 10:05:30
Modify Date: 2023-04-05 10:05:30
MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders[1].

Name	MALT1-IN-11

Description	MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> NF-κB >> MALT1 Research Areas >> Inflammation/Immunology
In Vitro	MALT1-IN-11 (Example 151, 24 h) 抑制 OCI-LY10 细胞中 IL10 的分泌[1]。
References	[1]. Shulu FENG, et al. Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disoders. Patent. WO2022164789.

Molecular Formula	C₂₀H₁₆F₄N₈O
Molecular Weight	460.39