675190-57-5

675190-57-5 structure

Name: NSD3-IN-2
Chemical Name: NSD3-IN-2
CAS Number: 675190-57-5
Molecular Formula: C₁₇H₁₅N₅OS
Molecular Weight: 337.40
Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
Create Date: 2023-04-13 16:24:41
Modify Date: 2024-04-11 12:11:41
NSD3-IN-2 is a potent NSD3 inhibitor with an IC50 value of 17.97 μM. NSD3-IN-2 inhibits the growth and proliferation of non-small cell lung cancer cell lines H460, H1299 and H1650 with anti-cancer activity[1].

Name	NSD3-IN-2

Description	NSD3-IN-2 is a potent NSD3 inhibitor with an IC50 value of 17.97 μM. NSD3-IN-2 inhibits the growth and proliferation of non-small cell lung cancer cell lines H460, H1299 and H1650 with anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
In Vitro	NSD3-IN-2 (化合物 C6) (30 μM; 48 h) 抑制 H460、H1299、H1560 细胞中 H3K36me3 的表达[1]。 NSD3-IN-2 (50 μM; 7-16 d) 抑制 H460、H1299、H1560 细胞增殖，但对 A549 细胞无抑制作用[1]。
References	[1]. Piao Lianhua, et al. Application of compound C6 as histone methyltransferase NSD3 inhibitor: China, CN109223794[P].2019-01-18.

Molecular Formula	C₁₇H₁₅N₅OS
Molecular Weight	337.40