NSD3-IN-2

Modify Date: 2024-04-11 12:11:41

NSD3-IN-2 Structure
NSD3-IN-2 structure
Common Name NSD3-IN-2
CAS Number 675190-57-5 Molecular Weight 337.40
Density N/A Boiling Point N/A
Molecular Formula C17H15N5OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NSD3-IN-2


NSD3-IN-2 is a potent NSD3 inhibitor with an IC50 value of 17.97 μM. NSD3-IN-2 inhibits the growth and proliferation of non-small cell lung cancer cell lines H460, H1299 and H1650 with anti-cancer activity[1].

 Names

Name NSD3-IN-2

 NSD3-IN-2 Biological Activity

Description NSD3-IN-2 is a potent NSD3 inhibitor with an IC50 value of 17.97 μM. NSD3-IN-2 inhibits the growth and proliferation of non-small cell lung cancer cell lines H460, H1299 and H1650 with anti-cancer activity[1].
Related Catalog
In Vitro NSD3-IN-2 (化合物 C6) (30 μM; 48 h) 抑制 H460、H1299、H1560 细胞中 H3K36me3 的表达[1]。 NSD3-IN-2 (50 μM; 7-16 d) 抑制 H460、H1299、H1560 细胞增殖,但对 A549 细胞无抑制作用[1]。
References

[1]. Piao Lianhua, et al. Application of compound C6 as histone methyltransferase NSD3 inhibitor: China, CN109223794[P].2019-01-18.

 Chemical & Physical Properties

Molecular Formula C17H15N5OS
Molecular Weight 337.40