1623012-10-1

1623012-10-1 structure

Name: Tanshinol borneol ester
Chemical Name: Tanshinol borneol ester
CAS Number: 1623012-10-1
Molecular Formula: C₁₉H₂₆O₅
Molecular Weight: 334.41
Catalog: Signaling Pathways Epigenetics AMPK
Create Date: 2023-06-18 17:30:47
Modify Date: 2024-04-06 09:52:01
Tanshinol borneol ester, an angiogenesis stimulator, promoted multiple key steps of angiogenesis through Akt and MAPK signalling pathways. Tanshinol borneol ester has anti-ischemic and anti-atherosclerosis activities[1].

Name	Tanshinol borneol ester

Description	Tanshinol borneol ester, an angiogenesis stimulator, promoted multiple key steps of angiogenesis through Akt and MAPK signalling pathways. Tanshinol borneol ester has anti-ischemic and anti-atherosclerosis activities[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Cardiovascular Disease Signaling Pathways >> PI3K/Akt/mTOR >> Akt Signaling Pathways >> PI3K/Akt/mTOR >> AMPK
Target	Akt AMPK
In Vivo	Tanshinol borneol ester (DBZ; 0.2, 1, 5 mg/kg; 腹腔给药; 每天; 8 天) 显着增加了血液含量和微血管形成[1]。 Animal Model: C57BL/6 mouse Matrigel plug model[1] Dosage: 0.2, 1, and 5 mg/kg Administration: IP; daily; 8 days Result: Produced significant increases in blood content compared with vehicle control, while no significant increase in haemoglobin content at the highest dose (25 mg/kg). Significantly increased microvessel formation.
References	[1]. Sha Liao, et al. Tanshinol borneol ester, a novel synthetic small molecule angiogenesis stimulator inspired by botanical formulations for angina pectoris. [2]. Pu Jia, et al. The anti-atherosclerotic effect of tanshinol borneol ester using fecal metabolomics based on liquid chromatography-mass spectrometry. Analyst. 2016 Feb 7;141(3):1112-20.

Molecular Formula	C₁₉H₂₆O₅
Molecular Weight	334.41