Shanghai Nianxing Industrial Co., Ltd
China
Product Name: b-Yohimbine
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: b-Yohimbine
Price: ￥3400.0/5mg
Purity: 98.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: b-Yohimbine
Price: ￥4000.0/5mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: beta-Yohimbine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16α,17β)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

549-84-8

549-84-8 structure

549-84-8 structure

Name: b-Yohimbine
Chemical Name: .β.-Yohimbine
CAS Number: 549-84-8
Molecular Formula: C₂₁H₂₆N₂O₃
Molecular Weight: 354.443
Catalog: Natural product Alkaloid
Create Date: 2018-08-21 14:18:34
Modify Date: 2024-01-06 20:13:24
β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A)-resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL)[1].

Name	.β.-Yohimbine
Synonyms	Methyl (16α,17β)-17-hydroxyyohimban-16-carboxylate Yohimban-16α-carboxylic acid, 17β-hydroxy-, methyl ester Yohimban-16-α-carboxylic acid, 17-β-hydroxy-, methyl ester .beta.-Yohimbine Amsonin Yohimban-16α-carboxylic acid, 17β-hydroxy-, methyl ester (8CI) Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16α,17β)- Amsonine b-Yohimbine β-Yohimbine

Description	β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A)-resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL)[1].
Related Catalog	Research Areas >> Infection
References	[1]. dos Santos Torres ZE, et al. Chemical composition of Aspidosperma ulei Markgr. and antiplasmodial activity of selected indole alkaloids. Molecules. 2013 May 29;18(6):6281-97.

Density	1.3±0.1 g/cm3
Boiling Point	543.0±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₆N₂O₃
Molecular Weight	354.443
Flash Point	282.2±30.1 °C
Exact Mass	354.194336
PSA	65.56000
LogP	2.20
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.661

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZG1000030

CHEMICAL NAME :: Yohimban-16-alpha-carboxylic acid, 17-beta-hydroxy-, methyl ester

CAS REGISTRY NUMBER :: 549-84-8

LAST UPDATED :: 199007

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C21-H26-N2-O3

MOLECULAR WEIGHT :: 354.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,317,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 68 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 94,17,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5400 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 94,17,1989

Hazard Codes	Xi

Precursor 0
DownStream 1
146-48-5