503614-92-4

503614-92-4 structure

Name: 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid
Chemical Name: 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylic acid
CAS Number: 503614-92-4
Molecular Formula: C₂₅H₂₄N₄O₅
Molecular Weight: 460.482
Create Date: 2018-12-10 09:07:35
Modify Date: 2026-07-08 21:23:36

Name	1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylic acid
Synonyms	Apixaban Impurity A / Apixaban Cboxylic Acid Impurity Apixaban-5 Apixaban Impurity BMS-591455-01 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-cboxylic acid 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-cboxylicaci 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-cboxylic Acid- 13C, D3 Apixaban Impurity SS 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c] Apixaban acid impuity 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1- piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-cboxylic acid methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo 3,4-clpyridine-3-cboxylic acid Apixaban Cboxylic Acid Apixaban impurity 2/1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-cboxylic acid 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-cboxylic acid Impurity of apixaban379 Apixaban ImpurityMS-591455-01 Apixaban Acid 503-4 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-cboxylic acid APIXABAN ACID IMP Apixaban Impurity 1(Cboxylic Acid )(BMS-591455-01) Apixaban Acid Impurity Apixaban impurity 01 Impurity of apixaban1719 Apixaban Cboxylic Acid Imp TECO-010 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-cboxylic acid 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihy Apixaban Cboxylic Acid Impurity Apixaban Impurity A 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-cboxylic acid Apixaban Impurity 41 (BMS-591455-01) Apixaban Impurity A (BMS-591455-01) Apixaban iMpurity(BMS-591455 Apixaban Impurity 1（Cboxylic Acid ） 1H-Pyrazolo[3,4-c]pyridine-3-cboxylic acid, 4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl] BMS-589154-01

Density	1.4±0.1 g/cm3
Boiling Point	807.2±65.0 °C at 760 mmHg
Molecular Formula	C₂₅H₂₄N₄O₅
Molecular Weight	460.482
Flash Point	442.0±34.3 °C
Exact Mass	460.174683
PSA	104.97000
LogP	1.63
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.695

675-20-7

473927-64-9

~30%

503614-91-3

503614-92-4

Literature: ZENTIVA, K.S.; HEJTMANKOVA, Ludmila; JIRMAN, Josef Patent: WO2014/75648 A1, 2014 ; Location in patent: Page/Page column 13 ;

385425-15-0

148-24-3

503614-56-0

503614-92-4

Literature: Zhou, Jiacheng; Oh, Lynette M.; Ma, Philip; Li, Hui-Yin; Confalone, Pasquale Patent: US2003/181466 A1, 2003 ;

27143-07-3

503614-92-4

Literature: ZENTIVA, K.S.; HEJTMANKOVA, Ludmila; JIRMAN, Josef Patent: WO2014/75648 A1, 2014 ;

473927-69-4

503614-92-4

Literature: ZENTIVA, K.S.; HEJTMANKOVA, Ludmila; JIRMAN, Josef Patent: WO2014/75648 A1, 2014 ;

Precursor 7
675-20-7 473927-64-9 385425-15-0 148-24-3
503614-56-0 27143-07-3 473927-69-4
DownStream 0

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