27143-07-3
27143-07-3 structure
- Name: Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate
- Chemical Name: ethyl (2Z)-2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate
- CAS Number: 27143-07-3
- Molecular Formula: C11H13ClN2O3
- Molecular Weight: 256.685
- Create Date: 2018-11-26 17:14:29
- Modify Date: 2026-06-30 11:44:59
| Name | ethyl (2Z)-2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate |
|---|---|
| Synonyms |
ethyl 2-chloro-2-[(4-methoxyphenyl)hydrazono]acetate
(4-methoxyphenyl) hydrazino] chloroacetic acid ethyl ester 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene] Apixaban Impurity 18 Ethyl-2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (Intermediate of Apixaban) Apixaban-2 hydrazono) 2-chloro-2-[2-(4-Methoxyphenyl)hydrazinylidene], ethyl ester (Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (Apixaban) Ethyl 2-chloro-2-[2-(4-methyoxyphenyl)hydrazono]acetate Apixaban Intermediate 1 Ethyl 2-chloro-2-[2-(4-methoxyphenyl)hydrazineylidene]acetate ethyl2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene] Ethyl 2-chloro-2-(2-(4-methoxyphenyl) Ethyl chloro[(4-methoxyphenyl)hydrazono]acetat ethyl [(4-methoxyphenyl)hydrazono]chloroacetate Impurity of apixaban382 ethyl 2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate (Z)-Ethyl-2-C-2-(2-(4-Methoxy Phenyl) Hydrazone acetate Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl este Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Ethyl[(4-methoxyphenyl)hydrazino]chloroacetate 2-chloro-2-[2-(4-Methoxyphenyl)hydrazinylidene] acetic acid, ethyl ester Ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate Apixaban intermediates，Ethyl chloro[2-(4- methoxyphenyl)hydrazinylidene]acetate Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]acetate (Z)- Ethyl chloro[(4-Methoxyphenyl)hydrazono]acetate Ethyl(z)-2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate Ethyl 2-chloro-2-(2 -(4-methoxyphenyl)hydrazono)acetate chloro ester chloro-(4-methoxy-phenylhydrazono)-acetic acid ethyl ester Aceticacid,2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]-,ethylester,(8Z) Apixaban Impurity Ethyl [(4-methoxyphenyl)hydrazono]chloroacetate 1-(4-methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicboxamide ethyl chloro[2-(4-Methoxyphenyl)hydrazinylidene]acetate 1. 2-chloro-2-[2-(4-Methoxyphenyl)hydrazinylidene]acetic acid ethyl ester Apixaban ethyl chloroacetate RSYY（Avanafil)-43 Acetic acid,2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene],ethyl ester Acetic acid, chloro[(4-methoxyphenyl)hydrazono]-, ethyl ester ethyl chloro(p-methoxyphenylhydrazono)acetate Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester Ethyl chloro (Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate Apixaban Impurity B Chloro((4-Methoxyphenyl)hydrazone)acetic acid ethyl ester thyl chloro[2-(4-methoxyphenyl)hydrazinylidene]acetate RSYY（Avanafil)-38 ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-cboxylate，Aceticacid,2-chloro-2-[2-(4- methoxyphenyl)hydrazinylidene], ethyl ester (Z)-ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate Apixaban Impurity 27 (Mixture of Z and E Isomers) Apixaban Impurity 2 |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 349.0±44.0 °C at 760 mmHg |
| Melting Point | 94ºC |
| Molecular Formula | C11H13ClN2O3 |
| Molecular Weight | 256.685 |
| Flash Point | 164.8±28.4 °C |
| Exact Mass | 256.061462 |
| PSA | 59.92000 |
| LogP | 3.17 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.533 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2928000090 |
|
~%
27143-07-3 |
| Literature: Synthesis, , # 11 p. 1799 - 1803 |
|
~%
27143-07-3 |
| Literature: US2006/69258 A1, ; Page/Page column 11-12 ; |
|
~%
27143-07-3 |
| Literature: Farmaco, Edizione Scientifica, , vol. 40, # 4 p. 259 - 271 |
| Precursor 4 | |
|---|---|
| DownStream 3 | |
![1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester structure](https://image.chemsrc.com/caspic/346/503614-91-3.png)
![Ethyl 6-(4-iodophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate structure](https://image.chemsrc.com/caspic/029/473927-64-9.png)
![1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid structure](https://image.chemsrc.com/caspic/308/503614-92-4.png)
| HS Code | 2928000090 |
|---|---|
| Summary | 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |