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912970-67-3

912970-67-3 structure

912970-67-3 structure

Name: CARM1-IN-3
Chemical Name: CARM1-IN-3
CAS Number: 912970-67-3
Molecular Formula: C₂₄H₃₂N₄O₂
Molecular Weight: 408.54
Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
Create Date: 2023-10-07 16:59:02
Modify Date: 2024-01-17 23:29:58
CARM1-IN-3 (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 µM for CARM1 and CARM3, respectively[1].

Name	CARM1-IN-3

Description	CARM1-IN-3 (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 µM for CARM1 and CARM3, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	IC50: 0.07 µM (CARM1); >25 µM (CARM3)[1]
References	[1]. Wan H, et al. Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5063-6.

Molecular Formula	C₂₄H₃₂N₄O₂
Molecular Weight	408.54

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