CARM1-IN-3

Modify Date: 2025-08-27 05:37:14

CARM1-IN-3 structure	Common Name	CARM1-IN-3
	CAS Number	912970-67-3	Molecular Weight	408.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₃₂N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CARM1-IN-3

CARM1-IN-3 (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 µM for CARM1 and CARM3, respectively[1].

Name	CARM1-IN-3

Description	CARM1-IN-3 (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 µM for CARM1 and CARM3, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	IC50: 0.07 µM (CARM1); >25 µM (CARM3)[1]
References	[1]. Wan H, et al. Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5063-6.

Molecular Formula	C₂₄H₃₂N₄O₂
Molecular Weight	408.54
InChIKey	PFOQIHIIOLBCEQ-UHFFFAOYSA-N
SMILES	CNCCN1CCC(c2cc(C)c3nc(-c4c(OC)cccc4OC)[nH]c3c2)CC1

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