2289736-54-3

2289736-54-3 structure

Name: Enpp-1-IN-17
Chemical Name: Enpp-1-IN-17
CAS Number: 2289736-54-3
Molecular Formula: C₁₈H₂₄N₄O₂
Molecular Weight: 328.41
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2023-10-01 12:09:54
Modify Date: 2024-09-16 16:58:56
Enpp-1-IN-17 (example 274) is a potent ENPP1 inhibitor, with the inhibition constants (Ki values) toward cGAMP and ATP hydrolysis of 100 nM-1 μM and > 1 μM, respectively. The selectivity ratio for inhibition of cGAMP hydrolysis versus ATP hydrolysis is >6.4[1].

Name	Enpp-1-IN-17

Description	Enpp-1-IN-17 (example 274) is a potent ENPP1 inhibitor, with the inhibition constants (Ki values) toward cGAMP and ATP hydrolysis of 100 nM-1 μM and > 1 μM, respectively. The selectivity ratio for inhibition of cGAMP hydrolysis versus ATP hydrolysis is >6.4[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Infection
References	[1]. William Michael Gallatin, et al. Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitors and uses thereof. Patent, WO2019046778A1.

Molecular Formula	C₁₈H₂₄N₄O₂
Molecular Weight	328.41