Enpp-1-IN-17

Modify Date: 2024-09-16 16:58:56

Enpp-1-IN-17 Structure
Enpp-1-IN-17 structure
Common Name Enpp-1-IN-17
CAS Number 2289736-54-3 Molecular Weight 328.41
Density N/A Boiling Point N/A
Molecular Formula C18H24N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Enpp-1-IN-17


Enpp-1-IN-17 (example 274) is a potent ENPP1 inhibitor, with the inhibition constants (Ki values) toward cGAMP and ATP hydrolysis of 100 nM-1 μM and > 1 μM, respectively. The selectivity ratio for inhibition of cGAMP hydrolysis versus ATP hydrolysis is >6.4[1].

 Names

Name Enpp-1-IN-17

 Enpp-1-IN-17 Biological Activity

Description Enpp-1-IN-17 (example 274) is a potent ENPP1 inhibitor, with the inhibition constants (Ki values) toward cGAMP and ATP hydrolysis of 100 nM-1 μM and > 1 μM, respectively. The selectivity ratio for inhibition of cGAMP hydrolysis versus ATP hydrolysis is >6.4[1].
Related Catalog
References

[1]. William Michael Gallatin, et al. Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitors and uses thereof. Patent, WO2019046778A1.

 Chemical & Physical Properties

Molecular Formula C18H24N4O2
Molecular Weight 328.41
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