2925261-76-1

2925261-76-1 structure
2925261-76-1 structure
  • Name: hCAIX-IN-18
  • Chemical Name: hCAIX-IN-18
  • CAS Number: 2925261-76-1
  • Molecular Formula: C17H19ClN4O3S
  • Molecular Weight: 394.88
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
  • Create Date: 2023-10-09 19:50:04
  • Modify Date: 2024-04-12 19:39:02
  • hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. hCAIX-IN-18 can be used for cancer research[1].

Name hCAIX-IN-18
Description hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. hCAIX-IN-18 can be used for cancer research[1].
Related Catalog
Target

hCA I:3.5 nM (IC50)

hCA II:9.4 nM (IC50)

hCA IX:43 nM (IC50)

hCA XII:8.2 nM (IC50)

References

[1]. 1. Peerzada MN, et al. Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors. ACS Med Chem Lett. 2023 May 8;14(6):810-819.  

Molecular Formula C17H19ClN4O3S
Molecular Weight 394.88