hCAIX-IN-18

Modify Date: 2024-04-12 19:39:02

hCAIX-IN-18 Structure
hCAIX-IN-18 structure
Common Name hCAIX-IN-18
CAS Number 2925261-76-1 Molecular Weight 394.88
Density N/A Boiling Point N/A
Molecular Formula C17H19ClN4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of hCAIX-IN-18


hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. hCAIX-IN-18 can be used for cancer research[1].

 Names

Name hCAIX-IN-18

 hCAIX-IN-18 Biological Activity

Description hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. hCAIX-IN-18 can be used for cancer research[1].
Related Catalog
Target

hCA I:3.5 nM (IC50)

hCA II:9.4 nM (IC50)

hCA IX:43 nM (IC50)

hCA XII:8.2 nM (IC50)

References

[1]. 1. Peerzada MN, et al. Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors. ACS Med Chem Lett. 2023 May 8;14(6):810-819.  

 Chemical & Physical Properties

Molecular Formula C17H19ClN4O3S
Molecular Weight 394.88