2757469-20-6
2757469-20-6 structure
- Name: Immuno modulator-1
- Chemical Name: Immuno modulator-1
- CAS Number: 2757469-20-6
- Molecular Formula: C32H31FN6O4
- Molecular Weight: 582.62
- Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
- Create Date: 2023-09-24 17:48:03
- Modify Date: 2024-01-29 16:45:32
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Immuno modulator-1 (compound 22) inhibits TNFα and IL-2 secretion in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 and 26 nM, respectively. Immuno modulator-1 shows hERG potassium channel blocking effect, with Inhibitory percentage of 20% at 3 μM[1].
| Name | Immuno modulator-1 |
|---|
| Description | Immuno modulator-1 (compound 22) inhibits TNFα and IL-2 secretion in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 and 26 nM, respectively. Immuno modulator-1 shows hERG potassium channel blocking effect, with Inhibitory percentage of 20% at 3 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
IL-2 |
| References |
[1]. Chen Xiangyang, et al. Heterocyclic immunomodulator. Patent, WO2022007659A1. |
| Molecular Formula | C32H31FN6O4 |
|---|---|
| Molecular Weight | 582.62 |