2427608-43-1

2427608-43-1 structure

2427608-43-1 structure

Name: JAK1-IN-11
Chemical Name: JAK1-IN-11
CAS Number: 2427608-43-1
Molecular Formula: C₂₆H₃₆N₆O₄S
Molecular Weight: 528.67
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2023-10-13 08:25:33
Modify Date: 2024-01-12 10:09:56
JAK1-IN-11 (compound 11) is a potent inhibitor of JAK，with IC50s of 0.02 nM (JAK1)，and 0.44 nM (JAK2)，respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1].

Name	JAK1-IN-11

Description	JAK1-IN-11 (compound 11) is a potent inhibitor of JAK，with IC50s of 0.02 nM (JAK1)，and 0.44 nM (JAK2)，respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	IC50: 0.02 nM (JAK1) 和 0.44 nM (JAK2)[1]
References	[1]. Shen W. et al. Amide or sulfonamide substituted hydrazine derivative applied as JAK kinase inhibitor. China, CN110724142 A. 2020-01-24.

Molecular Formula	C₂₆H₃₆N₆O₄S
Molecular Weight	528.67