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2545974-71-6

2545974-71-6 structure

2545974-71-6 structure

Name: P2X3 antagonist 38
Chemical Name: P2X3 antagonist 38
CAS Number: 2545974-71-6
Molecular Formula: C₂₂H₂₅F₃N₆O₃
Molecular Weight: 478.47
Catalog: Signaling Pathways Membrane Transporter/Ion Channel P2X Receptor
Create Date: 2023-11-18 09:12:28
Modify Date: 2025-08-26 11:52:20
P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].

Name	P2X3 antagonist 38

Description	P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor
Target	P2X3 Receptor:0.132 μM (IC50)
References	[1]. YunFeng Chen, et al. N-carboxamidopyrazoline derivative serving as p2x3 receptor antagonist and applications. WO2022028154A1.

Molecular Formula	C₂₂H₂₅F₃N₆O₃
Molecular Weight	478.47

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